Fig. 3

Gene expression and pathways changes in erythroid-committed progenitors of NHD13 mice at various time points. A Erythroid-committed progenitors (ErPs) were sorted from mice of different genotypes at various time points, and RNA was extracted for transcriptome sequencing analysis. B A Venn diagram identifies genes that are significantly differentially expressed in ErPs from different time points in NHD13 mice, in comparison with their respective controls. The numbers of overlapping genes are also indicated. C Gene expression profiles of erythroid-committed progenitors from NHD13 mice at various time points were clustered into different gene clusters, with each cluster subjected to KEGG enrichment analysis. D Gene set scores for various signaling pathways in ErPs from NHD13 mice at different time points